Lymphovascular invasion in testicular germ cell tumors: clinicopathological correlates
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منابع مشابه
Lymphovascular invasion in testicular germ cell tumors: clinicopathological correlates
INTRODUCTION We assessed clinical-pathological correlates of lymphovascular invasion in testicular germ-cell tumors. MATERIAL AND METHODS Archived pathology specimens from 145 patients treated by radical orchiectomy for testicular germ cell tumors at our institution in 1995-2006 were reanalyzed by a dedicated urologic pathologist, and the corresponding medical records were reviewed. The assoc...
متن کاملBilateral testicular germ cell tumors.
Testicular cancer represents 1% to 1.5% of neoplasias in males and 5% of urologic tumors in general. The incidence of bilateral testicular tumors is 1-5%. Approximately one third of the cases are diagnosed as synchronous, while the other two thirds are diagnosed as metachronous tumors. Additionally, 5% of all patients diagnosed with testicular cancer may have contralateral intratubular germ cel...
متن کاملgenetics of testicular germ cell tumors
testicular germ cell tumor (tgct) is the most solid tumor in 20-40 years old man. tgct account for 95% of testicular tumors and represent a unique type of human cancer from several different perspectives. tgct arise by transformation of germ cells. the transformed germ cells exhibit ploripotentially to differentiate into embryonic. extra-embryonic, and somatic tissue types, and are highly sensi...
متن کاملEpigenetic Modifications in Testicular Germ Cell Tumors
Over the past decade, accumulating evidence has implicated the phenomenon of epigenetic dysregulation in a variety of cancers (Biermann and Steger, 2007). Defined as the heritable changes in gene function that are not attributable to changes in DNA sequence, epigenetics involve biochemical modifications to DNA regulatory elements as well as to the tail regions of histone proteins (Maekawa and W...
متن کاملUpdate on testicular germ cell tumors.
PURPOSE OF REVIEW This overview discusses several important developments in testicular germ cell tumors (TGCTs) over the past year. RECENT FINDINGS Genomic studies continue to investigate gene expression as possible markers for disease relapse and metastatic potential. Optimal treatment strategies for early-stage seminomas continue to evolve toward surveillance versus chemotherapy, although d...
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ژورنال
عنوان ژورنال: Central European Journal of Urology
سال: 2013
ISSN: 2080-4873
DOI: 10.5173/ceju.2013.03.art5